Blog 14 - What next for Verisense?

In Blog 14 we preview the next iteration of Verisense - Verisense Pulse+. Adding to it’s existing capabilities, the Verisense platform is now expanding it’s sensing capacity, opening up new avenues and routes to digital endpoints.

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Today, in the US, less than 3% of a patient’s experience is captured at a clinical trial because it mostly happens outside of doctors and hospital walls. Continuing to support the shift in healthcare from the ‘subjective’ to ‘objective’ measurement, wearables continue to offer robust data sets to improve treatment efficacy, offer profound insight that can be leveraged in pharma trial development and not forgetting it can be used across many therapeutic areas for deep insight and interpretation of adverse effects of new drug trials.

As these various bio-signals can be used to extract vital signs for health monitoring applications, Verisense is adding to its competence allowing further investigation of hidden bio-signal detection.

Verisense Pulse+ will provide photoplethysmogram (PPG), galvanic skin response (GSR), and an inertial measurement unit (IMU). Trials that require the need for participant heart rate and emotional responses in addition to their activity and sleep levels can now benefit from these biosignals on one wrist worn device, with no change required to the existing Verisense platform.

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Examples of these Biosignals:

  • Photoplethysmogram (PPG) - provides beat-to-beat heart rate measurements and heart rate variability (HRV). The verisense PPG sensor monitors heart rate by using light absorption to measure changes in participant capillary blood volume.

    • An important marker of the Autonomic Nervous System (ANS) balance especially in Alzheimer’s Disease is Heart Rate Variability (HRV), a measure of the time intervals between heartbeats. Also, HRV has been put forward as an index of cognitive function and stress. PPG capability has set the foundation for widespread passive and continuous monitoring of users’ heart rate and heart rate variability making it more useful to the trial patients and other stakeholders.

  • IMU (Inertial Measurement Unit) includes accelerometer and gyroscope, used by numerous applications to track activity and sleep metrics.

  • Galvanic Skin Response (GSR) sensors equipped to measure the skin conductance and the skin resistance/impedance, by measuring changes in sweat gland activity which can be used to assess the participant’s level of psychological and emotional arousal, stress, and other emotional responses. GSR is used for psychology clinical research and biofeedback, and it is starting to be employed in more clinical applications, including epilepsy.

Verisense Pulse+ will be released in the coming months, register your interest HERE:

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Blog 13 - Clinical Trials in Crisis